货号：05-446

品牌：Merck Millipore

规格：100Ug

目录价：￥6742.00

市场价格：￥5730.70

会员价格：￥5393.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-p75NTR (Neurotrophin Receptor) Antibody, clone ME20.4 | 05-446 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: low affinity p75NTR View All» Molecular Weight: 69kDa View All» Immunogen: Human melanoma cell line WM245. View All» Clone: A16/17 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Monkey
  View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from HS294T cells View All» Purification Method: Protein G chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P08138 View All» Entrez Gene Number: NM_002507 View All» Gene Symbol:
  • NGFR

  • Gp80-LNGFR

  • CD271

  • p75(NTR)

  • TNFRSF16
    View All» Alternate Names: p75 Low Affinity Neurotrophin Receptor; NGFR View All» Sales Restrictions: Due to license agreement restrictions, this product cannot be purchased for resale. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunohistochemistry

    • Neutralizing
      View All» Entrez Gene Summary: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. View All» UniProt Summary: FUNCTION: SwissProt: P08138 # Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.SIZE: 427 amino acids; 45183 Da SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.DOMAIN: SwissProt: P08138 Death domain is responsible for interaction with RANBP9.PTM: N- and O-glycosylated. & O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. & Phosphorylated on serine residues.SIMILARITY: Contains 1 death domain. & Contains 4 TNFR-Cys repeats. View All» Brand Family: Upstate View All» Product Name: Anti-p75NTR (Neurotrophin Receptor) Antibody, clone ME20.4 | 05-446 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Plasma membrane View All» Format: Purified View All» Host: Mouse View All»
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      © Merck Millipore代理05-446 Anti-p75NTR (Neurotrophin Receptor) Antibody, clone ME20.4;抗-p75NTR（神经营养因子受体）抗体，克隆ME20.4store at -20，产品报价联系微信jinshanbio