Merck Millipore代理05-466 Anti-GRK 4-6 Antibody, clone A16/17;store at -20℃

2025-06-28

货号:05-466

品牌:Merck Millipore

规格:200Ug

目录价:¥5513.00

市场价格:¥4686.05

会员价格:¥4410.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-GRK 4-6 Antibody, clone A16/17 | 05-466 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: GRK 4, GRK 5 and GRK 6 View All» Molecular Weight: 65-70kDa View All» Immunogen: GST fusion protein corresponding to residues 463-590 of bovine GRK 5 View All» Isotype: IgG1κ View All» Species Reactivity:

  • Human

  • Mouse

  • Rat

    View All» Quality Assurance: routinely evaluated by immunoblot on murine 3T3/A31 RIPA lysate or human K562 cells View All» Purification Method: Ammonium sulfate precipitation View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15 NaCl with 0.05% sodium azide View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P32298 View All» Entrez Gene Number: NM_019497 View All» Gene Symbol:
    • GRK4

    • GRK4a

    • IT11

    • GPRK4

    • GPRK2L

    • ITI1

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunoprecipitation

      • Western Blotting

        View All» Entrez Gene Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. View All» UniProt Summary: FUNCTION: SwissProt: P32298 # Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin.SIZE: 578 amino acids; 66583 Da TISSUE SPECIFICITY: Testis, and in a lower extent in other tissues including brain cortex and striatum.SIMILARITY: SwissProt: P32298 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain. View All» Brand Family: Upstate View All» Product Name: Anti-GRK 4-6 Antibody, clone A16/17 | 05-466 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Mouse View All»

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