货号：05-550

品牌：Merck Millipore

规格：

目录价：￥3908.00

市场价格：￥3321.80

会员价格：￥3126.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cdc6 Antibody, clone DCS-180 | 05-550 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: cdc6 View All» Molecular Weight: 62kDa View All» Immunogen: Recombinant, full-length human cdc6 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: routinely evaluated by immunoblot on HeLa nuclear extract or 3T3 nuclear extract View All» Purification Method: Protein G chromatography View All» Presentation: 10mM PBS, pH 7.4 and 0.05% sodium azide View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q99741 View All» Entrez Gene Number: NM_001254 View All» Gene Symbol:
  • CDC6

  • HsCDC18

  • cdc6

  • HsCDC6

  • p62

  • CDC18L
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. View All» UniProt Summary: FUNCTION: SwissProt: Q99741 # Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.SIZE: 560 amino acids; 62720 Da SUBUNIT: Interacts with PCNA, ORC1L and cyclin-CDK.SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells.SIMILARITY: SwissProt: Q99741 ## Belongs to the CDC6/cdc18 family. View All» Brand Family: Upstate View All» Product Name: Anti-Cdc6 Antibody, clone DCS-180 | 05-550 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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