货号：05-555

品牌：Merck Millipore

规格：200Ug

目录价：￥4396.00

市场价格：￥3736.60

会员价格：￥3516.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Giα1 Antibody, clone 7H7 | 05-555 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Giα1 View All» Molecular Weight: 41kDa View All» Immunogen: Peptide corresponding to residues 110-123 of Giα1 View All» Clone: 7H7 View All» Isotype: IgG2b View All» Species Reactivity: Vertebrates View All» Quality Assurance: routinely evaluated by immunoblot on rat brain microsomal preparation View All» Purification Method: Protein G chromatography View All» Presentation: 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, containing 30% glycerol View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P63096 View All» Entrez Gene Number: NM_002069 View All» Gene Symbol:

• GNAI1

• Gi
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P63096 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.SIZE: 354 amino acids; 40361 Da SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity).SIMILARITY: SwissProt: P63096 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily. View All» Brand Family: Upstate View All» Product Name: Anti-Giα1 Antibody, clone 7H7 | 05-555 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Mouse View All»
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