货号：05-563

品牌：Merck Millipore

规格：

目录价：￥4891.00

市场价格：￥4157.35

会员价格：￥3912.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RBP1 Antibody, clone LY11 | 05-563 View All» Replaces: CBL447 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: RBP1 View All» Molecular Weight: 190kDa View All» Immunogen: GST fusion-protein corresponding to residues 154-679 of human RBP1. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Monkey
  View All» Quality Assurance: routinely evaluated by immunoblot on Jurkat nuclear extract View All» Purification Method: Protein A chromatography View All» Presentation: PBS and 0.03% thimerosol before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P06400 View All» Entrez Gene Number: NM_002892 View All» Gene Symbol:
  • RBP1

  • PP110

  • OSRC

  • P105-RB

  • retinoblastoma-1

  • retinoblastoma suspectibility protein

  • Retinoblastoma-associated protein
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Electrophoretic Mobility Shift Assay

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: Key regulator of entry into cell division that acts as a tumor suppressor. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting chromatin-modifying enzymes to promoters. Inhibits the intrinsic kinase activity of TAF1. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. View All» UniProt Summary: Size: 928 amino acids; 106159 Da Subunit: Interacts preferentially with transcription factor E2F1. The unphosphorylated form iinteracts with ARID3B, JARID1A, SUV39H1, MJD2A/JHDM3A and THOC1.Interacts with the N-terminal domain of TAF1. Interacts with AATF, DNMT1, LIN9, LMNA, SUV420H1, SUV420H2, PELP1 and TMPO-alpha.May interact with KNTC2. Interacts with EID1 and ZUBR1. Interacts with ARID4A and JARID1B Subcellular location: Nucleus View All» Brand Family: Upstate View All» Product Name: Anti-RBP1 Antibody, clone LY11 | 05-563 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Mouse View All»
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