货号：05-587

品牌：Merck Millipore

规格：

目录价：￥4090.00

市场价格：￥3476.50

会员价格：￥3272.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-Adducin (Ser724) Antibody, clone pADD | 05-587 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: phospho-Adducin isoforms View All» Molecular Weight: 80-120kDa View All» Immunogen: peptide (FRTP[pS]FLKK) corresponding to amino acids 720-728 of rat phospho-α-Adducin (Ser724) View All» Modifications: Phosphorylation View All» Clone: pADD View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot on lysates from human red blood cells stimulated with PMA View All» Purification Method: Protein G chromatography View All» Presentation: 0.7M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol. View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P35611 View All» Entrez Gene Number: NM_001119 and others View All» Gene Symbol:
  • ADD1

  • ADDA

  • Alpha-adducin

  • MGC44427

  • MGC3339
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. View All» UniProt Summary: FUNCTION: SwissProt: P35611 # Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.SIZE: 737 amino acids; 80955 Da SUBUNIT: Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit. Binds ROCK1.SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.TISSUE SPECIFICITY: Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.DOMAIN: SwissProt: P35611 Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.PTM: The N-terminus is blocked.SIMILARITY: Belongs to the aldolase class II family. Adducin subfamily. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-Adducin (Ser724) Antibody, clone pADD | 05-587 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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