货号：05-623

品牌：Merck Millipore

规格：200Ug

目录价：￥5268.00

市场价格：￥4477.80

会员价格：￥4214.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RNA polymerase II Antibody, clone CTD4H8 | 05-623 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: This antibody recognizes Phospho- and non-phospho-RNA polymerase II. View All» Molecular Weight: 210-220 kDa View All» Immunogen: Peptide containing 10 repeats of YSPT[pS]PS corresponding to the carboxyl-terminal domain of RNA polymerase II. View All» Clone: CTD4H8 View All» Isotype: IgG1 View All» Background Information: RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. The DNA binding domain of the polymerase is a groove where TFIIB orients the DNA for unwinding and transcription. View All» Species Reactivity:

• Human

• Rat

• Mouse

• Yeast (S. cerevisiae)
  View All» Species Reactivity Note: Human, mouse, rat and yeast. View All» Control: A431 nuclear extract. View All» Quality Assurance: Routinely evaluated by western blot on HeLa nuclear extracts. Western Blot Analysis: 0.05-1 μg/mL of this lot detected RNA polymerase II in HeLa nuclear extracts. 0.1-2 μg/mL of a previous lot detected RNA polymerase II in 3T3 nuclear extracts View All» Purification Method: Protein G chromatography View All» Presentation: Purified mouse IgG1 in buffer containing 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: P24928 View All» Entrez Gene Number: NP_000928 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • ChIP-seq
    View All» Brand Family: Upstate View All» Product Name: Anti-RNA polymerase II Antibody, clone CTD4H8 | 05-623 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Mouse View All»
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    © Merck Millipore代理05-623 Anti-RNA polymerase II Antibody, clone CTD4H8;抗RNA聚合酶II抗体，克隆CTD4H8store at -20℃，产品报价联系微信jinshanbio