货号：05-775

品牌：Merck Millipore

规格：

目录价：￥4048.00

市场价格：￥3440.80

会员价格：￥3238.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ha-Ras Antibody, clone MC57 | 05-775 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Ha-Ras; does not cross react with Cdc42, Rho or Rac1 View All» Molecular Weight: ~21kDa View All» Immunogen: GST fusion protein corresponding to full length human Ha-Ras View All» Isotype: IgG View All» Species Reactivity: Human View All» Species Reactivity Note: Predicted to cross-react with mouse and rat based on sequence homology. View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from A431 cells View All» Purification Method: Protein A purfied View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P01112 View All» Entrez Gene Number: NM_005343 View All» Gene Symbol:

• HRAS

• Ha-Ras

• K-ras

• N-ras

• p21ras

• CTLO

• HRAS1

• c-bas/has

• H-Ras-1

• RASH1

• c-H-ras

• H-RasIDX
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: P01112 # Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.SIZE: 189 amino acids; 21298 Da SUBUNIT: In its GTP-bound form interacts with PLCE1. Interacts with TBC1D10C. Interacts with RGL3 (By similarity).SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus.PTM: Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.DISEASE: SwissProt: P01112 # Defects in HRAS are the cause of Costello syndrome [MIM:218040]; also known as faciocutaneoskeletal syndrome. Costello syndrome is a rare condition characterized by prenatally increased growth, postnatal growth deficiency, mental retardation, distinctive facial appearance, cardiovascular abnormalities (typically pulmonic stenosis, hypertrophic cardiomyopathy and/or atrial tachycardia), tumor predisposition, skin and musculoskeletal abnormalities. & Mutations which change positions 12, 13 or 61 activate the potential of c-ras to transform cultured cells and are implicated in a variety of human tumors. & Defects in HRAS are a cause of bladder cancer [MIM:109800]. & Defects in HRAS are also the cause of oral squamous cell carcinoma (OSCC).SIMILARITY: SwissProt: P01112 ## Belongs to the small GTPase superfamily. Ras family. View All» Brand Family: Upstate View All» Product Name: Anti-Ha-Ras Antibody, clone MC57 | 05-775 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：https://www.16ao.com/thread-134029.htm
  © Merck Millipore代理05-775 ANTI-HA-RAS, PC 12-301，产品报价联系微信jinshanbio