货号：05-867

品牌：Merck Millipore

规格：

目录价：￥3381.00

市场价格：￥2873.85

会员价格：￥2704.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-C4bpα/β, clone GMA-036 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: C4bp, α and β subunits View All» Immunogen: purified human C4bpα/β View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Purification Method: DEAE chromatography View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number:

• P04003

• P20851
  View All» Entrez Gene Number: NM_000715, NM_000716 View All» Gene Symbol:
  • C4BPA

  • C4BP

  • PRP

  • C4bp
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: ELISA View All» Entrez Gene Summary: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. View All» UniProt Summary: FUNCTION: SwissProt: P20851 # Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.SIZE: 252 amino acids; 28357 Da SUBUNIT: Disulfide-linked complex of alpha and beta chains of 3 possible sorts: a 570 kDa complex of 7 alpha chains and 1 beta chain, a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. The central body of the alpha chain homopolymer supports tentacles, each with the binding site for C4b at the end.SUBCELLULAR LOCATION: Secreted.SIMILARITY: SwissProt: P20851 ## Contains 3 Sushi (CCP/SCR) domains. View All» Brand Family: Upstate View All» Product Name: Anti-C4bpα/β, clone GMA-036 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-134104.htm
    © Merck Millipore代理05-867 a-C4bpa/b, cl GMA-036 100ug，产品报价联系微信jinshanbio