货号：05-906

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cdc27, clone AF 3.1 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: cdc27 View All» Molecular Weight: Mr 97kDa View All» Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 821-830 (CQLHAAESDEF) of human cdc27 View All» Species Reactivity:

• Mammals

• Xenopus
  View All» Quality Assurance: routinely evaluated by immunoblot on HeLa nuclear extracts View All» Purification Method: Ascites View All» Storage Conditions: stable 2 years at -20°C from date of shipment View All» UniProt Number: P30260 View All» Entrez Gene Number: NM_001256.2 View All» Gene Symbol:
  • CDC27

  • CDC27Hs

  • D17S978E

  • H-NUC

  • HNUC

  • APC3

  • D0S1430E
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: SIZE: 824 amino acids; 91867 Da SUBUNIT: Interacts with RB.SUBCELLULAR LOCATION: Nucleus.PTM: Phosphorylated. Phosphorylation on Ser-426 and Thr-446 occurs specifically during mitosis.SIMILARITY: SwissProt: P30260 ## Belongs to the CDC27/NUC2 family. & Contains 9 TPR repeats. View All» Brand Family: Upstate View All» Product Name: Anti-Cdc27, clone AF 3.1 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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