货号：05-924

品牌：Merck Millipore

规格：EA

目录价：￥3468.00

市场价格：￥2947.80

会员价格：￥2774.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GFI1 Antibody, clone 2.5D.17 | 05-924 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: GFI1 View All» Molecular Weight: 55-65kDa View All» Immunogen: GST-fusion protein corresponding to residues 1-250 of rat growth factor independence-1 (GFI1). View All» Clone: 2.5D.17 View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Non-Reactive Species: Mouse View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Protein G purfied View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: Q99684 View All» Entrez Gene Number: NP_036698 View All» Gene Symbol:
  • GFI1

  • ZNF163
    View All» Alternate Names: Growth Factor Independent 1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: SwissProt: Q99684 # May be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. May be involved in tumor progression (By similarity). Represses ELA2 transcription.SIZE: 422 amino acids; 45297 Da SUBUNIT: Interacts with U2AF1L4 (By similarity).SUBCELLULAR LOCATION: Nucleus.DOMAIN:SwissProt: Q99684 The Gly/Ala-rich region may indicate that Gfi-1 is a repressor of its target genes.DISEASE: SwissProt: Q99684 # Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) [MIM:202700]. & Defects in GFI1 are a cause of dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA) [MIM:607847]. NI-CINA is a relatively mild form of neutropenia diagnosed in adults, but predisposing to leukemia in a subset of patients.SIMILARITY: Contains 6 C2H2-type zinc fingers. View All» Brand Family: Upstate View All» Product Name: Anti-GFI1 Antibody, clone 2.5D.17 | 05-924 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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