Merck Millipore代理05-935 Anti-ORC1, clone 7A7 50ug;已停产

2025-06-27

货号:05-935

品牌:Merck Millipore

规格:EA

目录价:询价

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-ORC1 Antibody, clone 7A7 | 05-935 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: ORC1 View All» Molecular Weight: 105kDa. Additional low MW bands were also detected. View All» Immunogen: Full-length human origin recognition complex 1 (ORC1). Clone 7A7. View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Protein G purfied View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: Q13415 View All» Entrez Gene Number: NM_004153 View All» Gene Symbol:

  • ORC1L

  • HSORC1

  • ORC1

  • PARC1

    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

      View All» Entrez Gene Summary: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. View All» UniProt Summary: FUNCTION: SwissProt: Q13415 # Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner.SIZE: 861 amino acids; 97350 Da SUBUNIT: ORC is composed of six subunits. Interacts with CDC6 and MYST2/HBO1.SUBCELLULAR LOCATION: Nucleus.SIMILARITY: SwissProt: Q13415 ## Belongs to the ORC1 family. & Contains 1 BAH domain. View All» Brand Family: Upstate View All» Product Name: Anti-ORC1 Antibody, clone 7A7 | 05-935 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Purified View All» Host: Rat View All»

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