货号：06-1025

品牌：Merck Millipore

规格：EA

目录价：￥4164.00

市场价格：￥3539.40

会员价格：￥3331.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-NET39 Antibody | 06-1025 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes NET39 at the cytoplasmic domain. View All» Molecular Weight: ~ 29 kDa observed. The band at ~23 kDa is uncharacterized, but may represent a possible isoform of this protein . (Malik, P., et al. (2010). View All» Epitope: Cytoplasmic domain View All» Immunogen: KLH-conjugated linear peptide corresponding to human NET39 at the cytoplasmic domain. View All» Background Information: NET39 (nuclear envelope transmembrane protein 39) also known as Probable lipid phosphate phosphatase PPAPDC3, has been shown to play a part in regulation of signaling and gene expression. By effecting mTOR signaling, NET39 has a negative regulatory effect on myoblast differentiation. It is predominantly expressed in cardiac and skeletal muscle. During myoblast differentiation, NET39 is highly upregulated. NET39 has been found to be an important part of regulation for myogenesis and might also be involved in muscle homeostasis. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected NET39 in A431 and HeLa cells. View All» Control: Rat liver tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat liver tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected NET39 on 10 µg of rat liver tissue lysate. Note: Western blot performed without Tween. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8NBV4 View All» Entrez Gene Number: NP_116117 View All» Gene Symbol:
  • PPAPDC3

  • NET39
    View All» Alternate Names:
    • phosphatidic acid phosphatase type 2 domain containing 3

    • chromosome 9 open reading frame 67

    • probable lipid phosphate phosphatase PPAPDC3

    • Phosphatidic acid phosphatase type 2 domain-containing protein 3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity).SUBUNIT STRUCTURE: Homo and heterooligomer. Interacts with MTOR; controls MTOR-dependent IGF2 expression during myoblast differentiation (By similarity).SUBCELLULAR LOCATION: Nucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein. Note: Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm (By similarity).SEQUENCE SIMILARITIES: Belongs to the PA-phosphatase related phosphoesterase family.SEQUENCE CAUTION: The sequence CAI16274.1 differs from that shown. Reason: Erroneous gene model prediction. View All» Product Name: Anti-NET39 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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