货号：06-1026

品牌：Merck Millipore

规格：

目录价：￥4621.00

市场价格：￥3927.85

会员价格：￥3696.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TM7SF2 Antibody | 06-1026 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~50 kDa observed View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human TM7SF2. View All» Background Information: Sterol Delta-14 reductase, also known as TM7SF2 and NET47, is important in the conversion of lanosterol to cholesterol, an essential cellular metabolic process, in many mammalian species. This protein is a multipass membrane protein typically found in the endoplasmic reticulum. View All» Species Reactivity:

• Human

• Bovine

• Rhesus Macaque
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with bovine and rhesus monkey based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in HeLa cells. (Image courtesy of Dr. Eric C. Schirmer, The Wellcome Trust Centre for Cell Biology, University of Edinburgh) View All» Control: Human brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human brain tissue lysate.Western Blot Analysis: 5 µg/mL of this antibody detected TM7SF2 on 10 µg of human brain tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O76062 View All» Entrez Gene Number: NP_003264.2 View All» Gene Symbol:
  • TM7SF2

  • ANG1

  • NET47
    View All» Alternate Names:
    • Delta(14)-sterol reductase

    • Delta-14-SR

    • Another new gene 1 protein

    • C-14 sterol reductase

    • Putative sterol reductase SR-1

    • Sterol C14-reductase

    • Transmembrane 7 superfamily member 2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Involved in the conversion of lanosterol to cholesterol.CATALYTIC ACTIVITY: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein TISSUE SPECIFICTY: Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. SEQUENCE SIMILARITIES: Belongs to the ERG4/ERG24 family.SEQUENCE CAUTION: The sequence AAC21450.1 differs from that shown. Reason: Sequencing errors.The sequence AAC21457.1 differs from that shown. Reason: Sequencing errors. View All» Product Name: Anti-TM7SF2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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