货号：06-1097

品牌：Merck Millipore

规格：

目录价：￥3346.00

市场价格：￥2844.10

会员价格：￥2676.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Jagged2 Antibody | 06-1097 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Jagged2 at the cytoplasmic domain. View All» Molecular Weight: 133 kDa calculated View All» Epitope: Cytoplasmic View All» Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Jagged2. View All» Background Information: Jagged 2 is a notch ligand belonging to the Notch gene family and is a necessary component for embryonic development. Notch is the receptor for Delta and Jagged ligands, which cause proteolysis of notch to liberate the intracellular domain. It is expressed in the heart, placenta and skeletal muscle and some expression is found in the pancreas, brain, lung, liver and kidney. Mutations in Jagged2 may be associated with multiple myeloma. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. Other homologies: Rat (83% sequence homology). Mouse (75% sequence homology). View All» Application Notes: Specificity confirmed with direct ELISA. View All» Control: Ductal carcinoma in situ tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in ductal carcinoma in situ tissue.Immunohistochemistry Analysis: 1:500 dilution of this antibody detected Jagged2 in ductal carcinoma in situ tissue. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y219 View All» Entrez Gene Number: NP_002217 View All» Gene Symbol:

• HJ2

• SER2

• JAG2
  View All» Alternate Names:
  • jagged 2

  • Jagged2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry (Paraffin)

    • ELISA
      View All» Entrez Gene Summary: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICTY: Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.SEQUENCE SIMILARITIES: Contains 1 DSL domain.Contains 16 EGF-like domains.Contains 1 VWFC domain. View All» Product Name: Anti-Jagged2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-134249.htm
      © Merck Millipore代理06-1097 Anti-Jagged2 (rabbit polyclonal)，产品报价联系微信jinshanbio