货号：06-1287

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DAI Antibody | 06-1287 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes DAI. View All» Molecular Weight: ~55 kDa observed. A non-specific bands may be observed at ~70 & 35 kDa (Karayel, E., et al. (2009). Eur. J. Immunol. 39:1–8). View All» Epitope: Unknown View All» Immunogen: Recombinant protein corresponding to mouse DAI. View All» Background Information: DNA-dependent activator of IFN regulatory factors (DAI), also known as DLM-1/ZBP1, belongs to the Zipcode-binding protein (ZBP) family. This family of proteins regulate the stability and localization of their target mRNA. It is expressed during embryonic development, but repressed in normal adult tissue. When re-activated, it has been detected in tumors such as breast, colon, and non-small cell carcinomas. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Control: LPS-treated (positive control) and untreated (negative control) RAW264.7 cell lysate View All» Quality Assurance: Evaluated by Western Blot in LPS untreated and treated RAW264.7 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody was used in 10 µg of LPS-treated (positive control) and untreated (negative control) RAW264.7 cell lysate for the purpose of detecting DAI. View All» Purification Method: Protein G purfied View All» Presentation: Purified rabbit polyclonal in PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9QY24 View All» Entrez Gene Number: NP_001132991 View All» Gene Symbol:

• DLM1

• DLM-1

• DAI

• ZBP1
  View All» Alternate Names:
  • Z-DNA binding protein 1

  • chromosome 20 open reading frame 183

  • DNA-dependent activator of IRFs

  • DNA-dependent activator of interferon regulatory factors

  • Tumor stroma and activated macrophage protein DLM-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: May play a role in host defense against tumors and pathogens. Binds Z-DNA.TISSUE SPECIFICITY: Expressed in lung, spleen and liver. Lower levels were seen in heart, kidney and testis. Expression is greatly up-regulated in tumor stromal cells and activated macrophages.INDUCTION: By interferon gamma and lipopolysaccharides (LPS).SEQUENCE SIMLARITIES: Contains 2 DRADA repeats. View All» Product Name: Anti-DAI View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rabbit View All»
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