货号：06-1296

品牌：Merck Millipore

规格：EA

目录价：￥3468.00

市场价格：￥2947.80

会员价格：￥2774.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MCM4 Antibody | 06-1296 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes MCM4 at and around the N-terminus. View All» Molecular Weight: ~97 kDa View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to residues surrounding the N-terminus of human MCM4. View All» Background Information: MCM4, minichrome maintenance deficient 4 (S. cerevisae), belongs to the super family AAA ATPase. There are 6 MCM proteins (2-7). The MCM complex is essential for initiation and DNA replication but their mechanism for regulation is poorly understood. The MCM protein family has been found in all eukaryotes but not in prokaryotes except for a MCM related protein found in Archaea. Each MCM subunit has a different affinity for one another forming its own subcomplex. MCM4, MCM6, and MCM7 bind together to form a trimeric complex sometimes referred to as the MCM core. View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: Proven to react with human and rat. View All» Application Notes: Western Blot Analysis: A 1:1,000 dilution from a previous lot detected MCM4 in A431, Hek293, HeLa, HepG2, Jurkat, and PC3 cell lysates. View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected MCM4 in 10 µg of HeLa cell lysate. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P33991 View All» Entrez Gene Number: NP_005905.1 View All» Gene Symbol:
  • CDC21

  • CDC54

  • MGC33310

  • P1-CDC21

  • P1-Cdc21

  • hCdc21
    View All» Alternate Names:
    • CDC21 homolog

    • DNA replication licensing factor MCM4

    • MCM4 minichromosome maintenance deficient 4

    • MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)

    • homolog of S. pombe cell devision cycle 21

    • minichromosome maintenance complex component 4

    • minichromosome maintenance deficient 4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Involved in the control of DNA replication.SUBCELLULAR LOCATION: Nucleus By similarity. SEQUENCE SIMILARITIES: Belongs to the MCM family.Contains 1 MCM domain. View All» Product Name: Anti-MCM4 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Unpurified View All» Host: Rabbit View All»
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