货号：06-1344

品牌：Merck Millipore

规格：

目录价：￥3433.00

市场价格：￥2918.05

会员价格：￥2746.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-NLRP13 Antibody | 06-1344 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~119 kDa observed. An uncharacterized band appears at ~90 kDa in some lysates. View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human NLRP13. View All» Background Information: NLRP13, also known as NALP13, is a member of the NALP family of cytoplasmic proteins. NALPs have been associated with activating caspase-1 using toll-like receptors (TLRs) during the immune response. The specific function of NLRP13 is unknown. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected NLRP13 in NIH/3T3 cells. View All» Control: C2C12 cell lysate View All» Quality Assurance: Evaluated by Western Blot in C2C12 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected NLRP13 on 10 µg of C2C12 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q86W25 View All» Entrez Gene Number: NP_789780 View All» Gene Symbol:
  • NOD14

  • NALP13

  • PAN13

  • NLRP13
    View All» Alternate Names:
    • NLR family, pyrin domain containing 13

    • Nucleotide-binding oligomerization domain protein 14

    • NACHT, leucine rich repeat and PYD containing 13

    • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13

    • NACHT, LRR and PYD containing protein 13

    • NACHT, LRR and PYD domains-containing protein 13
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» Entrez Gene Summary: Summary: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]. View All» UniProt Summary: FUNCTION: Involved in inflammation Potential.SEQUENCE SIMILARITIES: Belongs to the NLRP family.Contains 1 DAPIN domain.Contains 7 LRR (leucine-rich) repeats.Contains 1 NACHT domain. View All» Product Name: Anti-NLRP13 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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