货号：06-1372

品牌：Merck Millipore

规格：100UL

目录价：￥5475.00

市场价格：￥4653.75

会员价格：￥4380.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-acetyl (Lys26) phospho (Ser27) Histone H1.4 Antibody | 06-1372 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the N-terminus of Histone H1.4 acetylated at Lys26 and phosphorylated at Ser27. View All» Molecular Weight: ~35 kDa observed. Uncharacterized bands may be observed at ~70 kDa and ~17 kDa in some acid extracts. View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H1.4 acetylated at Lys26 and phosphorylated at Ser27. View All» Background Information: H1.4 is one of four variants of histone H1 (H1.2-H1.5) that is found in somatic cells. The H1 histones may function as linker proteins binding DNA via their GH domain, and enabling the wrapping of DNA around the core nucleosomal structure formed from the association of H2A, H2B, H3, and H4. In response to various stimuli, histones undergo a number of post-translational modifications (PTM) including acetylation, phoshorylation, and methylation. Previous studies have suggested that H1.4 may be phosphorylated during mitosis and interphase resulting in increased transcription of target genes by RNA polymerase I and II, and therefore this PTM on H1.4 may have implications for cell growth. H1.4 may also undergo acetylation of its N-terminal lysine residues. Often, it is the pattern of different modifications on several histone residues that alter chromatin and affect gene expression, rather than modification of single residues. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Canine, Orangutan, Giant Panda, and Rhesus Macaque based on 100% sequence homology. Other homologies: Rat and Mouse (82% sequence homology). View All» Application Notes: Dot Blot Analysis: A 1:1,320 dilution from representative lot detected acetyl (Lys26) phospho (Ser27) Histone H1.4 peptides. View All» Control: Colcemid treated HeLa acid extract View All» Quality Assurance: Evaluated by Western Blot in colcemid treated HeLa acid extract.Western Blot Analysis: A 1:3,000 dilution of this antibody detected acetyl (Lys26) phospho (Ser27) Histone H1.4 in 10 µg of colcemid treated HeLa acid extract. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P10412 View All» Entrez Gene Number: NP_005312 View All» Gene Symbol:

• HIST1H1E

• H1F4
  View All» Alternate Names:
  • Histone H1.4

  • Histone H1b
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Dot Blot
      View All» Product Name: Anti-acetyl (Lys26) phospho (Ser27) Histone H1.4 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-134313.htm
      © Merck Millipore代理06-1372 Anti-acetyl (Lys26) phospho (Ser27) Histone H1.4 Antibody;store at +2℃ to +8℃，产品报价联系微信jinshanbio