货号：06-415

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Bcl-3 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Product Overview: This antibody works well on Bcl3 transfected cell lysates; it does not effectively blot endogenous levels of Bcl3 from RIPA cell lysates View All» Specificity: Bcl3 View All» Molecular Weight: 47kDa View All» Immunogen: Fusion protein containing amino acid residues 290-421 of human Bcl-3 View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: routinely evaluated by immunoblot on a Bcl3 transfected Cos-1 cell lysate View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P20749 View All» Entrez Gene Number: NM_033601 View All» Gene Symbol:

• BCL3

• D19S37

• BCL4
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunoprecipitation

  • Western Blotting

  • Immunocytochemistry
    View All» Entrez Gene Summary: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. View All» UniProt Summary: FUNCTION: SwissProt: P20749 # Could be a transcriptional activating factor. Functions as a form of I-kappa-B specific for NF-kappa-B p50 subunit inhibiting its translocation to the nucleus.SIZE: 446 amino acids; 46800 Da SUBUNIT: Interacts with N4BP2 and COPS5.SUBCELLULAR LOCATION: Nucleus.PTM: Activated by phosphorylation.DISEASE:SwissProt: P20749 # A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(14;19)(q32;q13.1) with immunoglobulin gene regions.SIMILARITY: SwissProt: P20749 ## Contains 7 ANK repeats. View All» Brand Family: Upstate View All» Product Name: Anti-Bcl-3 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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