货号：06-480

品牌：Merck Millipore

规格：

目录价：￥4528.00

市场价格：￥3848.80

会员价格：￥3622.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cathepsin B Antibody | 06-480 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes procathepsin B and mature cathepsin B. View All» Molecular Weight: procathepsin B (40 kDa) and mature cathepsin B (25 kDa, 26 kDa and 30 kDa) View All» Immunogen: Recombinant rat procathepsin B 1 View All» Isotype: IgG View All» Species Reactivity:

• Mouse

• Rat
  View All» Control: A431 Cell Lysate View All» Quality Assurance: routinely evaluated by immunoblot on rat kidney microsomal preparation (Catalog #12-146) View All» Purification Method: Protein A purfied View All» Presentation: Protein A Purified immunoglobulin. 0.1 M Tris-Glycine, 0.15 M NaCl, 0.05% sodium azide, pH 7.4. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P07858 View All» Entrez Gene Number: NM_001908 View All» Gene Symbol:
  • CTSB

  • CPSB

  • APPS
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P07858 # Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.SIZE: 339 amino acids; 37822 Da SUBUNIT: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.SUBCELLULAR LOCATION: Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.SIMILARITY: SwissProt: P07858 ## Belongs to the peptidase C1 family. View All» Brand Family: Upstate View All» Product Name: Anti-Cathepsin B Antibody | 06-480 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 400 μg View All» Target / Localization: Dedifferentiated chondrocytes View All» Format: Purified View All» Host: Rabbit View All» Packaging: 2 vials of 200 μg View All»
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