Merck Millipore代理06-676 Anti-mGluR2/3 Antibody;store at -20℃

2025-06-27

货号:06-676

品牌:Merck Millipore

规格:200Ug

目录价:¥6127.00

市场价格:¥5207.95

会员价格:¥4901.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-mGluR2/3 Antibody | 06-676 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: mGluR2 and mGluR3 View All» Molecular Weight: 100-110kDa View All» Immunogen: peptide (KQFVPTVCNGREVVDSTTSSL) corresponding to amino acids 853-872 of human metabotropic glutamate receptor 2 View All» Isotype: IgG View All» Species Reactivity:

  • Mouse

  • Rat

    View All» Quality Assurance: routinely evaluated by immunoblot on rat brain microsomal preparation View All» Purification Method: Protein A chromatography View All» Presentation: 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q14416 View All» Entrez Gene Number: NM_000839 / NM_000840 View All» Gene Symbol:
    • GRM2

    • GPRC1B

    • MGLUR2

    • GLUR2

    • mGlu2

    • mGluR2

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Immunoprecipitation

      • Western Blotting

        View All» Entrez Gene Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. View All» UniProt Summary: FUNCTION: SwissProt: Q14416 # Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.SIZE: 872 amino acids; 95568 Da SUBUNIT: Interacts with GRASP (By similarity).SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Widely expressed in different regions of the adult brain as well as in fetal brain.SIMILARITY: SwissProt: Q14416 ## Belongs to the G-protein coupled receptor 3 family. View All» Brand Family: Upstate View All» Product Name: Anti-mGluR2/3 Antibody | 06-676 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»

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