货号：06-967

品牌：Merck Millipore

规格：EA

目录价：￥3460.00

市场价格：￥2941.00

会员价格：￥2768.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Gab2 Antibody | 06-967 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes Gab2. View All» Molecular Weight: 95 kDa View All» Immunogen: GST fusion-protein corresponding to residues 285-676 of human Gab2 View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Control: HeLa cell lysate View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from rat L6, Baf3 or Hela cells View All» Purification Method: Protein A purfied View All» Presentation: Protein G Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: Q9UQC2 View All» Entrez Gene Number: NM_080491 View All» Gene Symbol:
  • GAB2

  • p97

  • KIAA0571

  • pp100
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. View All» UniProt Summary: SIZE: 676 amino acids; 74458 Da SUBUNIT: Interacts with GRB2, PI-3 kinase and with other SH2- containing proteins.PTM: Phosphorylated on tyrosine residue(s) by the thrombopoietin receptor (TPOR), stem cell factor receptor (SCFR), and T-cell and B-cell antigen receptors, gp130, IL-2R and IL-3R. & Dephosphorylated by PTPN11.SIMILARITY: SwissProt: Q9UQC2 ## Belongs to the GAB family. & Contains 1 PH domain. View All» Brand Family: Upstate View All» Product Name: Anti-Gab2 Antibody | 06-967 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 μg View All» Format: Purified View All» Host: Rabbit View All»
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