货号：07-1227

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PDE1B, Calmodulin-Dependent Phosphodiesterase 1B1 View All» Replaces: 07-1227 is a recommended replacement for AB1655. View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Distinguishes 1B1, a less abundant gene isoform of CaM-PDE in most tissues, from 1A2. View All» Molecular Weight: 61 kDa View All» Immunogen: Synthetic peptide (CEEAPSSPAEDEHN) coupled to KLH. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Human, Mouse and Rat. View All» Application Notes: Immunohistochemisty (paraffin): Representative testing from a previous lot.Optimal Staining of PDE1 Polyclonal Antibody: Ovarian Cancer PDE1 staining pattern in ovarian cancer, tissue was pretreated with citrate buffer, pH 6.0. A previous lot of this antibody was diluted to 1:100, using IHC-Select® detection with HRP-DAB.Immunoprecipitation: 3 µL per reaction of a previous lot of this antibody was used in Immunoprecipitation.Western Blot: A previous lot of this antibody was tested on multiple lysates. See datasheet. View All» Control: PC12 cell lysate View All» Quality Assurance: Routinely evaluated by Western Blot on PC12 lysates. Western Blot Analysis: 1:500-1:1,000 dilution of this lot detected PDE1B on 10 μg of PC12 lysates. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal IgG in buffer containing TBS, pH 8, containing 40% glycerol as a cryopreservative. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt in undiluted aliquots; at this temperature the solution will remain unfrozen.Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage. View All» UniProt Number: Q01064 View All» Entrez Gene Number: NM_000924 View All» Gene Symbol:
  • PDE1B

  • PDE1B1

  • Phosphodiesterase-1B

  • PDES1B

  • EC 3.1.4.17
    View All» Alternate Names:
    • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

    • Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase

    • Calmodulin-stimulated phosphodiesterase PDE1B1

    • phosphodiesterase 1B, calmodulin-dependent

    • Presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B 2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation

      • Immunohistochemistry (Paraffin)
        View All» UniProt Summary: FUNCTION: SwissProt: Q01064 # Has a preference for cGMP as a substrate.SIZE: 536 amino acids; 61380 Da SUBUNIT: Homodimer (By similarity).SUBCELLULAR LOCATION: Cytoplasm.SIMILARITY: SwissProt: Q01064 ## Belongs to the cyclic nucleotide phosphodiesterase family. View All» Product Name: Anti-PDE1B, Calmodulin-Dependent Phosphodiesterase 1B1 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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