金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Val23-Arg55 (B chain), with an N-terminal Met & Gln162-Cys185 (A chain) Accession #:P04090 N-terminal Sequence Analysis:Met (B chain) & Gln162 (A chain) Structure:Disulfide-linked heterodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:2.7 kDa (A chain), 3.9 kDa (B chain) Activity:Measured by its ability to induce cAMP accumulation in THP‑1 human acute monocytic leukemia cells. Parsell, D.A. et al. (1996) J. Biol. Chem. 271:27936.The ED₅₀ for this effect is typically0.5 -2.5 ng/mL. Molecule Information: Relaxin-2 Aliases: RLN2; RLXH2 Entrez Gene IDs: 6019 (Human) Background: Relaxins The Insulin/Relaxin superfamily includes Insulin, IGF-I, IGF-II, Relaxins, Relaxin-like Factor (RLF), Early Placenta Insulin-like Peptide 4 (INSL4), INSL5, and INSL6. Three human Relaxin genes (Relaxins-1 to -3) have been identified. Relaxin-2 is secreted and circulates in the blood, whereas Relaxin-1 is expressed in decidua, placenta, and prostate, and Relaxin-3 is expressed in the brain. Human Relaxin-2 is a peptide hormone that plays an important role in female reproduction.