金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Ser27-His901, with a C-terminal 10-His tag Accession #:Q9WVB4 N-terminal Sequence Analysis:Ser27 Purity:>80%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:99.1 kDa SDS-PAGE:115-130 kDa, reducing conditions Activity:Measured by its ability to enhance neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Able to significantly enhance neurite outgrowth when immobilized at 6-12 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.See Certificate of Analysis for details. Molecule Information: Slit3 Long Name: SLIT Homolog 3 Aliases: MEGF5; SLIL2 Entrez Gene IDs: 6586 (Human); 20564 (Mouse); 83467 (Rat) Background: Slit Ligands & ROBO Receptors Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are characterized structurally by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO4, a fourth putative family member, has been identified, but lacks one of the three fibronectin-like domains and two of the five Ig-like domains. ROBOs are best known for their roles as receptors for the Slit family of repellent axon guidance cues.