金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gly26-Gly318, with a C-terminal 6-His tag Accession #:Q6DFX2 N-terminal Sequence Analysis:Gly26 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:32 kDa SDS-PAGE:32-35 kDa, reducing conditions Activity:Measured by its ability to bind anthrax protective antigen (PA) in a functional ELISA. Scobie,H.M. etal. (2003) Proc. Natl. Acad. Sci. USA 100:5170.Immobilized PA at 1.5µg/mL (100µL/well) can bind rmCMG-2 with a linear range of 0.08-5.0µg/mL. Molecule Information: CMG-2/ANTXR2 Long Name: Capillary Morphogenesis Protein 2 Aliases: ANTXR2; cI-35; ISH; JHS Entrez Gene IDs: 118429 (Human); 71914 (Mouse) Background: CMG-2 CMG-2 is an anthrax toxin receptor (ATR) family protein that contains one von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment for anthrax.