金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:AAA18947 N-terminal Sequence Analysis:Asn27 Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:85.5 kDa (monomer) SDS-PAGE:120 kDa, reducing conditions Activity:Measured by its ability to inhibit Flt-3 Ligand-induced proliferation of BaF3 mouse pro‑B cells transfected with Flt-3.The ED₅₀ for this effect is typically 0.01 - 0.03 µg/mL in the presence of rhFlt-3 Ligand at 2 ng/mL. Molecule Information: Flt-3/Flk-2 Long Name: fms-like Tyrosine Kinase 3 Aliases: CD135; Flk-2; STK-1 Entrez Gene IDs: 2322 (Human); 14255 (Mouse) Background: Flt-3 The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.