货号：07-1407

品牌：Merck Millipore

规格：50Ug

目录价：￥5249.00

市场价格：￥4461.65

会员价格：￥4199.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GLUT-8 Antibody, C-terminus | 07-1407 View All» Replaces: AB3140 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes GLUT-8. View All» Molecular Weight: Approx. 50 kDa View All» Epitope: C-terminus View All» Immunogen: An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000) View All» Background Information: GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Reacts with human. Expected to react in mouse based on sequence homology. View All» Control: Human kidney tissue. View All» Quality Assurance: Evaluated by Immunohistochemistry in human kidney tissueImmunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in PBS with 0.1% BSA. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9NY64 View All» Entrez Gene Number: Q9NY64 View All» Gene Symbol:
  • GLUT-8

  • GLUT8

  • GLUTX1

  • OTTHUMP00000022176
    View All» Alternate Names:
    • Glucose transporter type 8

    • Glucose transporter type X1

    • glucose transporter X1

    • solute carrier family 2 (facilitated glucose transporter)member 8

    • solute carrier family 2 (facilitated glucose transporter),member 8
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry (Paraffin) View All» UniProt Summary: FUNCTION: Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose By similarity.SUBUNIT STRUCTURE: Interacts with AP2B1 By similarity.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein By similarity. Cytoplasmic vesicle membrane; Multi-pass membrane protein By similarity. Note: Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration By similarity.TISSUE SPECIFICITY: Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.INDUCTION: In testis, down-regulated by estrogen.SEQUENCE SIMILARITIES: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. [View classification] View All» Product Name: Anti-GLUT-8, C-terminus View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Rabbit View All»
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