货号：07-1408

品牌：Merck Millipore

规格：100UL

目录价：￥4592.00

市场价格：￥3903.20

会员价格：￥3673.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Glucose Regulating Protein 94 (GRP94) Antibody | 07-1408 View All» Replaces: 07-1408 is a recommended replacement for AB3545. View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Glucose regulating protein 94 (GRP94, Endoplasmin). View All» Molecular Weight: ~94 kDa View All» Immunogen: Peptide corresponding to an internal sequence from human GRP94. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Monkey

• Rat
  View All» Species Reactivity Note: Human, rat and monkey. Other species not tested. View All» Application Notes: Immunocytochemistry: Rabbit anti-GRP94 from a previous lot detected localization of GRP94 (green) in HEK293 cells. Blue staining is DAPI which stains the nucleus of the cell. Previous lots of this antibody showed positive testing for immunocytochemistry on HeLa, COS7 and HEK293 cells.Optimal working dilutions must be determined by the end userWestern Blot: A previous lot of this antibody was tested on multiple lysates. See datasheet. View All» Control: Jurkat cell lysate View All» Quality Assurance: Routinely evaluated by Western Blot on Jurkat lysates. Western Blot Analysis: 1:500-1:1,500 dilution of this lot detected GRP94 on 10 μg of Jurkat lysates. View All» Presentation: Rabbit polyclonal IgG serum in buffer containing 0.02% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C in undiluted aliquots from date of receipt.Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P14625 View All» Entrez Gene Number: NM_003299.1 View All» Gene Symbol:
  • HSP90B1

  • GP96

  • GRP94

  • TRA1

  • ECGP
    View All» Alternate Names:
    • 94 kDa glucose-regulated protein 3

    • Endoplasmin precursor 3

    • Heat shock protein 90 kDa beta member
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» Entrez Gene Summary: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]. View All» UniProt Summary: FUNCTION: Molecular chaperone that functions in the processing and transport of secreted proteins. Has ATPase activity (By similarity). SUBUNIT: Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5 (By similarity). Part a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. PTM: Phosphorylated (By similarity). SIMILARITY: Belongs to the heat shock protein 90 family. View All» Product Name: Anti-Glucose Regulating Protein 94 (GRP94) Antibody | 07-1408 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Serum View All» Host: Rabbit View All»
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