金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q96CY4 N-terminal Sequence Analysis:Cys32 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:72 kDa (monomer) SDS-PAGE:130-150 kDa, reducing conditions Activity:Measured by its ability to inhibit NT-3-induced proliferation of BaF‑TrkB‑BD mouse pro‑B cells transfected with TrkB.The ED₅₀ for this effect is typically 0.05 - 0.2 µg/mL in the presence of 40 ng/mL of rhNT-3. Molecule Information: TrkC Long Name: Neurotrophic Tyrosine Kinase Receptor C Aliases: NTRK3 Entrez Gene IDs: 4916 (Human); 18213 (Mouse); 29613 (Rat) Background: TrkC View TrkC IHC images. Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system.