货号：07-1463

品牌：Merck Millipore

规格：EA

目录价：￥3228.00

市场价格：￥2743.80

会员价格：￥2582.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Rho (-A, -B, -C) Antibody | 07-1463 View All» Replaces: AB3384 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes Rho-A, -B, -C. This antibody detects an ~22 kDa band, corresponding to the expected molecular weight of Rho. View All» Molecular Weight: 20 to 22 kDa View All» Immunogen: Synthetic peptide corresponding to human Rho. View All» Background Information: Rho proteins belong to the Ras super family of low molecular weight GTPases, which includes RAS, RHO, RAB, RAN, RAD and ARF. These small GTP binding proteins function as molecular switches that regulate a multitude of biological processes including cell proliferation, apoptosis, differentiation, cytoskeletal reorganization, and membrane trafficking. View All» Species Reactivity: Human View All» Species Reactivity Note: Proven to react with human. View All» Control: HL-60 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HL-60 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Rho on 10 µg of HL-60 cell lysate. View All» Purification Method: Protein A purfied View All» Presentation: Purified immunoglobulin in buffer containing 0.02 M phosphate buffer with 0.15 M NaCl, pH 7.6 and 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: Q92730 View All» Entrez Gene Number: NP_001655.1 View All» Gene Symbol:

• ARHS

• FLJ42294

• RHO6

• RHOS

• Rho6

• Rnd1
  View All» Alternate Names:
  • GTP-binding protein

  • GTP-binding protein RHO6

  • Rho family GTPase 1

  • ras homolog gene family, member S
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION:Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. SUBUNIT STRUCTURE: Binds GRB7 and PLXNB1. Interacts with UBXD5. SUBCELLULAR LOCATION:Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm › cytoskeleton Ref.9. TISSUE SPECIFICITY: Mostly expressed in brain and liver.SEQUENCE SIMILARITIES: Belongs to the small GTPase superfamily. Rho family. View All» Product Name: Anti-Rho (-A, -B, -C) Antibody | 07-1463 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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