金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ala2-Tyr478, with a C-terminal 10-His tag Accession #:P50579 N-terminal Sequence Analysis:Ala2 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:54 kDa SDS-PAGE:66 kDa, reducing conditions Activity:Measure by its ability to remove methionine from a fluorogenic peptide substrate H-Met-Gly-Pro-AMC (Catalog# ES017). The resulting GP-AMC is cleaved by Recombinant Human DPPIV/CD26 (Catalog# 1180-SE). The specific activity is >15 pmol/min/µg, as measured using the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: Methionine Aminopeptidase 2/METAP2 Aliases: Amp2; METAP2; MNPEP; p67eIF2 Entrez Gene IDs: 10988 (Human); 56307 (Mouse); 64370 (Rat) Background: METAP (Methionine Aminopeptidase) METAPs play a central role for protein maturation as they remove the initiator Met residue from newly synthesized proteins. Three METAP genes (METAP1, METAP2 and MAP1D) have been identified in the human genome. Fumagillin, a natural compound, covalently modifies an active His residue of METAP2 and prevents the vascularization and metasis of tumors.