金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P09581 N-terminal Sequence Analysis:Ala20 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:82.3 kDa (monomer) SDS-PAGE:115-135 kDa, reducing conditions Activity:Measured by its ability to inhibit the M-CSF-induced proliferation of NFS‑60 mouse myelogenous leukemia lymphoblast cells. Halenbeck, R. et al. (1989) Biotechnology 7:710.The ED₅₀ for this effect is typically 0. 2 - 0.8 µg/mL in the presence of 2.5 ng/mL mouse M-CSF. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: M-CSF R Long Name: Macrophage Colony Stimulating Factor Receptor Aliases: CD115; c-fms; CSF1R Entrez Gene IDs: 1436 (Human) Background: M-CSF Receptor (CD115) M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and the alpha and beta receptors for PDGF. M-CSF receptor is expressed primarily on cells of the monocyte/macrophage lineage and in various tissues of the developing placenta.