金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gln826-Ala1816, with a C-terminal 10-His tag Accession #:P97927 N-terminal Sequence Analysis:No result observed, predicted to start at Gln826 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:112.0kDa SDS-PAGE:105-115 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of HT1080 human fibrosarcoma cells.The ED₅₀ for this effect is typically1-4 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in Tris and NaCl, pH 6.0.See Certificate of Analysis for details. Molecule Information: Laminin alpha 4 Aliases: LAMA4 Entrez Gene IDs: 3910 (Human); 16775 (Mouse); 309816 (Rat) Background: Laminins Laminins are heterotrimeric, noncollagenous glycoproteins composed of combinations of five known alpha, four beta and three gamma chains in mammals. One alpha, beta and gamma subunit self-assembles to form at least 15 coiled-coil heterotrimers. Through specific interactions with integrins, dystroglycan, and other receptors, laminins contribute to cell differentation, cell shape and migration, maintenance of tissue phenotypes and survival. Some subunits, such as Laminin gamma1 (Laminin B2), are present in several laminins; Laminin-1 (EHS laminin), Laminin-2 (merosin), Laminin-3 (S-laminin), Laminin-4 (S-merosin), Laminin-6 (K-laminin) and Laminin-7 (KS-laminin). Others, such as the beta3 and gamma2 subunits, occur in only one known combination (e.g. with alpha3 in Laminin-5 / Epiligrin).