金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ala59-Asp128 Accession #:P02775 N-terminal Sequence Analysis:Ala59 Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:7.6 kDa Activity:Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. etal. (1987) J.Immunol. 139:3474.The ED₅₀ for this effect is typically 0.1-0.3 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR2.The ED₅₀ for this effect is typically 0.1-0.5 ng/mL. Molecule Information: CXCL7/NAP-2 Aliases: CTAP III; NAP-2; PPBP Entrez Gene IDs: 5473 (Human) Background: CXCL7/NAP-2 Neutrophil activating peptide 2 (NAP-2), connective tissue activating protein III (CTAP-III) and beta-thrombogulin (beta-TG), are proteolytically processed carboxy-terminal fragments of platelet basic protein (PBP), which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines and is named CXCL7. Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, NAP-2 binds CXCR2 and chemoattracts and activates neutrophils.