金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ala21-Ala89 Accession #:P55774.1 N-terminal Sequence Analysis:Ala21 Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:7.8 kDa Activity:Measured by its ability to inhibit Eotaxin-induced chemotaxis of BaF3 mouse pro‑B cells transfected with human CCR3. Nibbs, RJB. et al. (2000) J. Immunol. 164:1488.The ED₅₀ for this effect is typically 1 - 5 µg/mL.Measured by its ability to chemoattract resting human T lymphocytes.The ED₅₀ for this effect is typically0.5 -2 µg/mL. Molecule Information: CCL18/PARC Aliases: AMAC-1; DC-CK1; MIP-4; PARC Entrez Gene IDs: 6362 (Human) Background: CCL18/PARC (Pulmonary and Activation Regulated Chemokine) Pulmonary and activation-regulated chemokine (PARC), also known as alternative macrophage activation-associated CC chemokine (AMAC)-1, macrophage inflammatory protein (MIP)-4, and dendritic cell chemokine (DC-CK1), is a novel CC chemokine that is highly homologous to MIP-1 alpha (61% amino acid sequence identity). In vitro, PARC mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10 and IL-13, and inhibited by IFN-gamma.