金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Gly596-Val855, with an N-terminal Met and 6-His tag Accession #:NP_068813 N-terminal Sequence Analysis:Val615 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:26 kDa; Other fragments of 19 kDa, 17 kDa, 9 kDa and 6 kDa are also observed in the recombinantprotein preparation. SDS-PAGE:27 kDa (major), 20 kDa, 17 kDa,10 kDa, 6.5 kDa, reducing conditions Activity:Measured by its ability to cleave the fluorogenic peptide substrate Boc-QAR-AMC (Catalog# ES014).The specific activity is >10,000 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris-HCl and Glycerol.See Certificate of Analysis for details. Molecule Information: Matriptase/ST14 Aliases: Epithin; MTSP1; PRSS14; SNC19; ST14; TADG-15 Entrez Gene IDs: 6768 (Human); 19143 (Mouse); 114093 (Rat) Background: Matriptase Human matriptase, encoded by the ST14 (suppression of tumorogenicity 14) gene, is also known as tumor associated differentially expressed gene 15 protein/TADG-15), epithin, and membrane-type serine protease 1/MT-SP1. Predicted to have a significant role in tumor biology, matriptase may be a novel target for anti-cancer therapy. However, expressed in most human epithelia, matriptase is also important in several physiological processes. For example, it activates prostasin to initiate a protease cascade that is essential for epidermal differentiation, and it converts a single-chain IGFBP-rp1 into the two-chain form.