货号：07-1804

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Taf6 Antibody | 07-1804 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~68 kDa observed. Uncharacterized bands may appear at ~32 kDa and ~85 kDa in some lysates. View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to mouse Taf6. View All» Background Information: Fourteen TBP-associated factors (TAFs) and the TATA-binding protein (TBP) form the TFIID complex, which is used to recognize core promoters. TAF6 is known to have a histone fold domain (HFD) and is associated with histone H4. TAF6 is pivotal to the transcription of the p53 tumor suppressor protein and a splice variant of TAF6, TAF6delta, has been found to be essential for apoptosis signaling without p53. View All» Species Reactivity:

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Mouse. Predicted to react with Rat based on 100% sequence homology. Other homologies: Human (99% sequence homology). View All» Control: Mouse embryonic stem cell lysate View All» Quality Assurance: Evaluated by Western Blot in mouse embryonic stem cell lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected Taf6 in 10 µg of mouse embryonic stem cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q62311 View All» Entrez Gene Number: NP_033341 View All» Gene Symbol:
  • Taf6

  • Taf2e
    View All» Alternate Names:
    • Transcription initiation factor TFIID subunit 6

    • Transcription initiation factor TFIID 70 kDa subunit

    • TAF(II)70

    • TAFII-70

    • TAFII70

    • Transcription initiation factor TFIID 80 kDa subunit

    • TAF(II)80

    • TAFII-80

    • TAFII80

    • p80
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors (By similarity).SUBUNIT STRUCTURE: TFIID and PCAF are composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TBP is not part of TFTC. Interacts directly with TBP, TAF1/TAFII250, TAF9/TAFII31 AND TAF12/TAFII20. The TAF6/TAFII70-TAF9/TAFII31 heterodimer forms an octamer complex with the TAF4B/TFII105-TAF12/TFIID20 heterodimer. Also interacts with the GTFs, TFIIEalpha/GTF2E1 and TFIIFalpha/GTF2F1. Component of the TFTC-HAT complex. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10 (By similarity).SUBCELLULAR LOCATION: Nucleus. SEQUENCE SIMILARITIES: Belongs to the TAF6 family. View All» Product Name: Anti-Taf6 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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