货号：07-229

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TACC1 Antibody | 07-229 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: TACC1 View All» Molecular Weight: 125kDa View All» Immunogen: peptide corresponding to amino acids 219-235 (CPELVPSRRSKLRKPKP) of human TACC1 View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from HeLa cells View All» Purification Method: Immunoaffinity chromatography View All» Presentation: 2M Tris pH 8.0, 1.5M NaCl, 1mM EDTA, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: O75410 View All» Entrez Gene Number: NM_006283 View All» Gene Symbol:

• TACC1

• DKFZp686K18126

• Ga55

• KIAA1103
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunoprecipitation

  • Western Blotting
    View All» Entrez Gene Summary: The function of this gene has not yet been determined; however, it is speculated that it may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. View All» UniProt Summary: FUNCTION: SwissProt: O75410 # Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.SIZE: 805 amino acids; 87794 Da SUBUNIT: Interacts with KIAA0097/CH-TOG and with the oncogenic transcription factor YEATS4. Interacts with the Aurora kinases A and B (STK6 and AURKB). Interacts with LSM7, TDRD7 and SNRPG. Interacts with GCN5L2 and PCAF.SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosis.TISSUE SPECIFICITY: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues.DEVELOPMENTAL STAGE: Expressed at high level during early embryogenesis.PTM: Isoform 1 is heavily phosphorylated; isoform 6 is not. Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: O75410 ## Belongs to the TACC family. & Contains 2 SPAZ (Ser/Pro-rich AZU-1) domains. MISCELLANEOUS: Down-regulated in a subset of cases of breast cancer." View All» Brand Family: Upstate View All» Product Name: Anti-TACC1 Antibody | 07-229 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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