货号：07-231

品牌：Merck Millipore

规格：

目录价：￥3475.00

市场价格：￥2953.75

会员价格：￥2780.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-mTOR (mTAb1) Antibody | 07-231 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Product Overview: mTOR is also known as FRAP or RAFT View All» Specificity: Recognizes mTOR. View All» Molecular Weight: 240 kDa View All» Immunogen: peptide (C-DTNAKGNKRSRTRTDSYS) corresponding to amino acids 2433-2450 of rat mTOR, mammalian target of rapamycin View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Control: BDNF activated mTOR in dendritic, neural lysates or synaptoneurosomes View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from 293T cells transfected with mTOR View All» Purification Method: Immunoaffinity purified View All» Presentation: Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P42345 View All» Entrez Gene Number: NM_004958 View All» Gene Symbol:
  • FRAP1

  • RAPT1

  • MTOR

  • FRAP

  • mTOR

  • FLJ44809

  • FRAP2

  • RAFT1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Enzyme Assay

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The CDT6 gene is located in an intron of this gene. View All» UniProt Summary: FUNCTION: SwissProt: P42345 # Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.SIZE: 2549 amino acids; 288892 Da SUBUNIT: Interacts with the FKBP12-rapamycin complex. Binds UBQLN1. Forms part of the mammalian target of rapamycin 2 complex (TORC2) comprised of FRAP1, GBL, PRR5, RICTOR and SIN. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to PRR5 and RICTOR within the TORC2 complex.TISSUE SPECIFICITY: Expressed in numerous tissues, with highest levels in testis.SIMILARITY: SwissProt: P42345 ## Belongs to the PI3/PI4-kinase family. & Contains 1 FAT domain. & Contains 1 FATC domain. & Contains 7 HEAT repeats. & Contains 1 PI3K/PI4K domain. View All» Brand Family: Upstate View All» Product Name: Anti-mTOR (mTAb1) Antibody | 07-231 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 μL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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