货号：07-239

品牌：Merck Millipore

规格：200Ug

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-mGluR7 Antibody | 07-239 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: mGluR7 View All» Molecular Weight: 97kDa View All» Immunogen: peptide (C-NSPAAKKKYVSYNN) corresponding to amino acids 899-912 of human mGluR7 View All» Isotype: IgG View All» Species Reactivity: Rat View All» Quality Assurance: routinely evaluated by immunoblot on rat brain microsomal preparation View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q14831 View All» Entrez Gene Number: NM_000831 View All» Gene Symbol:

• GRM7

• GLUR7

• mGlu7

• mGluR7

• MGLUR7

• GPRC1G

• FLJ40498
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of GRM8 have been described but their full-length nature has not been determined. View All» UniProt Summary: FUNCTION: SwissProt: Q14831 # Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.SIZE: 915 amino acids; 102251 Da SUBUNIT: Interacts with PRKCABP (By similarity).SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.SIMILARITY: SwissProt: Q14831 ## Belongs to the G-protein coupled receptor 3 family. View All» Brand Family: Upstate View All» Product Name: Anti-mGluR7 Antibody | 07-239 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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