货号：07-262

品牌：Merck Millipore

规格：EA

目录价：￥3372.00

市场价格：￥2866.20

会员价格：￥2697.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Arg Antibody, SH3/SH2 | 07-262 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Arg View All» Molecular Weight: 135 & 140kDa View All» Immunogen: GST fusion protein corresponding to the SH2 and SH3 domains of murine Arg (Abl-related gene), residues 112-259 View All» Isotype: IgG View All» Species Reactivity: Mouse View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from Mouse Brain Cytosol View All» Purification Method: Immunoaffinity chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: P42684 View All» Entrez Gene Number: NM_136360 View All» Gene Symbol:

• ABL2

• Abelson-related

• ABLL

• ARG
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Immunoprecipitation

  • Western Blotting
    View All» Entrez Gene Summary: The gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.COFACTOR: Magnesium or manganese.SIZE: 1182 amino acids; 128343 Da SUBCELLULAR LOCATION: Cytoplasm.TISSUE SPECIFICITY: Widely expressed.PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain. View All» Brand Family: Upstate View All» Product Name: Anti-Arg Antibody, SH3/SH2 | 07-262 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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