金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Glu111-Lys540, with an N-terminal 6-His tag Accession #:NP_775736 N-terminal Sequence Analysis:His Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:41.9 kDa SDS-PAGE:55-65 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of SW1353 human chondrosarcoma cells.When 5 x 10⁴ cells/well are added to rhCOL23A1 coated plates (10 µg/mL, 100 µL/well), approximately 60% - 80% will adhere after 60 minutes at 37° C. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Collagen XXIII alpha 1 Aliases: COL23A1 Entrez Gene IDs: 91522 (Human); 237759 (Mouse); 353303 (Rat) Background: Collagen XXIII alpha 1 Collagen XXIII alpha 1 is a member of the collagenous transmembrane protein superfamily that includes collagens XIII, XVII, XXV and some non-collagens with triple-helical regions. Proteolytic cleavage by furin allows the collagen XXIII soluble ectodomain to be secreted. Collagen XXIII is concentrated at sites of cell contact in epithelia, and is thought to be an adhesion molecule. Its upregulation has been correlated with aggressiveness in transformed cells, particularly in prostate cancer.