R&D Systems代理419-ML-050/CF Recombinant Mouse IL-12 Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理419-ML-050/CF Recombinant Mouse IL-12 Protein, CF (50 UG)

2025-06-27

货号：419-ML-050/CF

品牌：R&D Systems

规格：50ug

目录价：￥11320.00

市场价格：￥9056.00

会员价格：￥9056.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived Accession #:P43432 (p40) & NP_032377 (p35) N-terminal Sequence Analysis:

Met23 (p40) & Arg23 (p35)

Structure:Disulfide-linked heterodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: SDS-PAGE:70 kDa, non-reducing conditions Activity:Measured in a cell proliferation assay using PHA-activated mouse splenocytes. Mattner, F. et al. (1993) Eur. J. Immunol. 23:2202.The ED₅₀ for this effect is typically 0.01 - 0.1 ng/mL. Molecule Information: IL-12 Long Name: Interleukin 12 Aliases: CLMF1; IL12A; NKSF1 Entrez Gene IDs: 3592 (Human); 16159 (Mouse); 84405 (Rat); 403977 (Canine); 493741 (Feline) Background: IL-12

View IL-12 IHC images. Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.

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