金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gln28-Ala326, with a C-terminal 10-His tag Accession #:O00602 N-terminal Sequence Analysis:Ala30 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:33.4 kDa SDS-PAGE:35-36 kDa, reducing conditions Activity:Measured by its ability to bind immobilized Fetuin in a functional ELISA. Liu,Y. et al. (2005) J. Immunol. 175:3150.The ED₅₀ for this effect is typically 0.01-0.04ng/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.See Certificate of Analysis for details. Molecule Information: Ficolin-1 Long Name: Ficolin [Collagen/Fibrinogen Domain Containing] 1 Aliases: FCN1; Fcna; FCNM Entrez Gene IDs: 2219 (Human); 14133 (Mouse) Background: Ficolins Ficolins-1 (M-ficolin), -2, and -3 are secreted pattern-recognition lectins that contribute to the innate immune recognition of pathogens. Ficolins have one fibrinogen-like domain and one collagen-like domain and circulate as disulfide-linked homo-oligomers. Following ligand binding, ficolins associate with MASP serine proteases to trigger the lectin complement cascade.