金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gln19-Arg483 (alpha) & Val484-Gly711 (Cys672Ala) (beta) Accession #:AAA59872 N-terminal Sequence Analysis:Gln19 & Val484 Structure:Disulfide-linked heterodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:53 kDa ( alpha -chain), 25 kDa ( beta -chain) SDS-PAGE:60 kDa and 30 kDa, reducing conditions Activity:Measured by its ability to activate MSPR/Ron in MDA-MB-453 or T47D human breast cancer cells.80 ng/mL of the rhMSP (C672A) significantly induces phosphorylation of MSP R/Ron measured by DuoSet^® IC human phopho-MSP R/Ron kit (R&D Systems, Catalog # DYC1947). Molecule Information: MSP/MST1 Long Name: Macrophage Stimulating Protein/Macrophage Stimulating 1 [Hepatocyte Growth Factor-like] Aliases: HGFL; MST1; SF2 Entrez Gene IDs: 4485 (Human); 15235 (Mouse); 24566 (Rat) Background: MSP Macrophage-stimulating protein (MSP), also known as Hepatocyte Growth Factor-like Protein (HGFL) and Scatter Factor-2 (SF2), is a member of the HGF family of growth factors. MSP is secreted as a single chain inactive precursor (pro-MSP). In response to injury, pro-MSP is activated by proteolytic cleavage. Activation results in the creation of alpha and beta chains joined by a disulfide bond.