金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived Accession #:P25446 N-terminal Sequence Analysis:Gly14 & Arg35 Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:46 kDa (monomer) SDS-PAGE:55 kDa, reducing conditions Activity:Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells.The ED₅₀ for this effect is typically 0.03-0.1µg/mL in the presence of 20ng/mL recombinant human Fas-ligand. Molecule Information: Fas/TNFRSF6/CD95 Long Name: Fibroblast-associated Aliases: Apo-1; APT1; CD95; TNFRSF6 Entrez Gene IDs: 355 (Human); 14102 (Mouse); 246097 (Rat); 493881 (Feline) Background: Fas/TNFRSF6 Fas (Fibroblast-associated), also known as Apo-1, CD95, and TNFRSF6, was originally identified as a cell-surface protein that binds to monoclonal antibodies that are cytolytic for various human cell lines. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas, have been identified. Fas is highly expressed in epithelial cells, hepatocyes, activated mature lymphocytes, virus-transformed lymphocytes and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary.