金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Met1-Val377, with an N-terminal Met and 7-His tag Accession #:AAH50433 N-terminal Sequence Analysis:No results obtained: Met predicted Purity:>85%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:43 kDa SDS-PAGE:48 kDa, reducing conditions Activity:Measured by its ability to remove the acetyl group from a fluorogenic peptide substrate Ac-RGK(Ac)-AMC (Catalog# ES016) in a coupled assay.The specific activity is >1.5 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: Histone Deacetylase 8/HDAC8 Aliases: HDAC8; HDACL1; RPD3 Entrez Gene IDs: 55869 (Human); 70315 (Mouse); 363481 (Rat) Background: Histone Deacetylase 8/HDAC8 Human Histone Deacetylase 8 (HDAC8) is a member of the class I histone Deacetylases (HDACs). Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor trichostatin A.

Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A