货号：07-479

品牌：Merck Millipore

规格：

目录价：￥3674.00

市场价格：￥3122.90

会员价格：￥2939.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CEA Receptor L View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: CEARL/hnRNP M4 isoform 1 View All» Molecular Weight: 74-80kDa View All» Immunogen: peptide corresponding to amino acids 161-182 of human carcinoembryonic antigen receptor long. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot in RIPA lysates from HeLa cells. View All» Purification Method: Protein A purfied View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P13688 View All» Gene Symbol:
  • CEACAM1

  • BGP-1

  • BGP

  • BGPI

  • CD66a

  • BGP1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. View All» UniProt Summary: SIZE: 526 amino acids; 57560 Da SUBCELLULAR LOCATION: Isoform A: Cell membrane; Single-pass type I membrane protein. & Isoform B: Cell membrane; Single-pass type I membrane protein. & Isoform C: Cell membrane; Single-pass type I membrane protein. & Isoform G: Secreted. & Isoform H: Secreted. & Isoform I: Secreted.DISEASE:SwissProt: P13688 # Loss or reduced expression is a major event in colorectal carcinogenesis. & Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders.SIMILARITY: SwissProt: P13688 ## Belongs to the immunoglobulin superfamily. CEA family. & Contains 3 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain. View All» Brand Family: Upstate View All» Product Name: Anti-CEA Receptor L View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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